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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6e13a7ab8833cd1743368a72f53c00458663a19d6bfe96bc3e8f225e27bcd2' 
  AND token = 'Ge6pZsQ5B5IeF4bSFnyRNSo1QImP/1i5r+/FCKHW6BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}