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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41765e79f208ed3f11dc5be9a7b2587d56e098ad55decebc23b816e3a2f3e156' 
  AND token = 'Vn/aNm2UsDpg7as3yudyLqOH2tm4KMWpyvgd26uQ3GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}