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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19685587b06fa81774c7116e89a2bbea69f2c28b9b41f30b00192d363d8bbc35' 
  AND token = '3LxKfjAaLzcT9M3/sv1/duTMRA+Jo6cHNsNh1MnWwzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}