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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd85d386954a15ae7cb0d6ea689fdfa5b1c0445376fd0295fc61760446a524156' 
  AND token = '4NbuudlKOgWbtyd297+8UPCaMiCT3z/lb04br34OsWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}