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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfed03bff6c6136fca6efc902c9a0ec93d13379a0bbcea379d07a87036a1b278' 
  AND token = 'glztSPcDueEnWAjPPZRr5se+ptzpqWgemaZVM9jlM2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}