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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20099d2ab183c9429b03542d21d1176021b4db3fba4a27d5dfa24d9eea878a63' 
  AND token = 'I72GDmUtiFQ4yikpyLbz+CXXV81XVLy8YEJD13LeTaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}