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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f9352fc69c56b2673df2f615dc4404795c56b7ff613611e9a1d89b42d0659d' 
  AND token = 'cXL+UNHgtt6lAXRmXHTBUSgY4jt4Xsk/O8B4/tzzDq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}