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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c59f9c6577a623520199aeb41d00d7cf0c424b04ef44c6e6bfbfb7151a40d91' 
  AND token = 'Te+R/EId7GOFxHQGVDcGtSLqA8Ai1zBwzT0BYssbbvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}