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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b603e906ff768c78f33a906a9cfb939d0f956b57638c8ab386bef265e36e2e4' 
  AND token = 'YSOPu6mDTQfVdpnb7+EwVov5UJTeVHE5wsRi+2JSe3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}