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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f18498146fbd036a535b9043bb7e8a5342f38989a5ff31bf0ac797811c9f683' 
  AND token = 'JArLjDuCgimxLDhVIf9g6T+UaA0y07gn+9RKPNubXL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}