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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4358a1a62cf7611edf179f6fc481b9855fe3be315705e7a31b8790f1c2bd04c5' 
  AND token = 'Yxi6P88otmKhT9iYhogtPtpEtBB/IYGOs1GbJagTEyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}