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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4965b3b177f6381440e90786054c4ee942eea93ac84f4a5aa777e836d7f88b05' 
  AND token = 'd9FHiDdjLNNhXoJ0t4I/oC5eEtydr/KJO/tgrkcgj9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}