Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef8fe6cb4ab5c11b31fafdd958af58482d0a9ac809e5ceecf86e9f71e56cf48' 
  AND token = 'tQRJO2SoFOMO7vPYo1xBbOnLFZzFOeGU3qzmWY+nAEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}