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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143230fcc48a0e411ddb96627de30a1b6bdf37ee52ed9f5ba06dbf2cc6d9924f' 
  AND token = 'ff9JNHCKU3+OQpwv7nn68LFsAt6DuBlpmFh2K39vHIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}