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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46315803a9cebc6b64335773eb721fa32065f370f8c8465c14520a1909249b9c' 
  AND token = 'VmDuO7WgeUP+rWRAVujJAvVneWtYbnMUIAjdwScl7yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}