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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa04c328468bd5c516ffa45220f40fdbfc32c1f216ab0aaa71c3357fff2bafa' 
  AND token = 'DY3RzQDZRD9+VDq2YtYIW3y0C4Jeg0FTxsZObwlk+Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}