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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af12ff84b030400cbb139b43d1d2e39da5a36931a950e341d677741e05de2693' 
  AND token = 'GUpfp/32c13OeByjH0l+YuwU5AxZjnG7Hzdh3/AXX2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}