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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f765ce106f6b16d8ad1bdb3b48e0995c0a0c490e61d04964bb077501478e92' 
  AND token = 'GKGPaPkjOaeydALBKahctY4SO2xAnHafcsXPjt3vdmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}