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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3cc00f376db568b60e8b0588c8557c196d6eca9ca5bd8084192ce1fec74553f' 
  AND token = '+ha3wwTL6cTx35jk4AjS23zrhgH3/AlhNLdlS4GUXio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}