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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3680b521cff64cc286c81e36c4fe226e080c85df29575d28f7579260284f03' 
  AND token = 'gz1SmQDlbdHxEov2Mk3G7U10aHDJb6CH29+wviT1WYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}