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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18a0001b52cb5cb78e616be3c351f60d0e2f268e68821f871542156eccc8cc5' 
  AND token = 'IsvoT32fGXCdGktWwb6t6uF+0L65f7esu0h5lJ/VPo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}