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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c80c2f4e15f116c00a320cb17516faf40e47deed4cc0475957929b719fee5fc' 
  AND token = 'VT1aWtCgeGHHfE37jXIgRjDDL5RdONJYOR7uhq67Tb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}