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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77fc955f0acb2b54bba9dc92a3c86135988d33950284dc5c42638e52551f2571' 
  AND token = 'DdJJixH6Z7GU6DvXcj9L5gq6evgE3izRIWqA6X3ScyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}