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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f49d5d3c2c6651de06ef7b1ae449383a26e2cae153b2a2cef55a25d10a1f8b8' 
  AND token = 'oOiLit0t+19tuCvIMIOx6ezUD8/YW8BaRFI7o/0vWQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}