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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3527ab75f5d4c6a0654e97cb1d7c735a204ab30e852a97f50cb02c00812f332d' 
  AND token = 'xCtOcmX5/ewafcqwnKP3L1YsPFdzRw5wfR8+jHlXS6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}