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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce48757d7cf3ab0f2970443515a3490823b3843cc749b031fe945b7a71e02c2d' 
  AND token = 'KlqU+2T0wfhnv9PXhrW1yPZaGtuogjF5dPsksn1M26I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}