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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a804144e0259950c69d188093e8f84e6316febd424926d261945d3e90fb6a82c' 
  AND token = 'x+DratYHgSl6pMGNYZ3Z1eDwD7fdYZnjvIHpLBHcjQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}