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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2949382a307a58c2a85e3245aed9dfbd2e8dc52d69c5c4dea7fe102aa0168283' 
  AND token = 'YChZ36kLMc5T+Z7W2GfC/dTT+sZxTN+vC3xfxKna69I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}