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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0373f6934f8d7c209b3fc11a38d68737cc221bee465df97b9b983ff753e6a3' 
  AND token = 'HpECJ8QQtTTTun7W2eYEVy0K2MooJoYHrEP7sA2pVrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}