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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104fc6c04da5326e3cded9ec7f8ff756a7433a9ef7856a2a074cdf5268742a64' 
  AND token = '74DbkdaRLL26KzUBQjuiCkOZZolf1aUiOb2rJ2FzC5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}