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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7e9b850a64bb630d8788eab6285d7328f2f284f03409c6e5610c608b6bce52' 
  AND token = 'jPDRXhG4PVGn9J5AaLGSQvWcPGubyFsoEma/8yWw+lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}