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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536529f9e6f71cd7d4771f7d9215a8544bc02527a1d9f4356e1928c64655e030' 
  AND token = 'ZaHOlyrVwFuFVRr7+rDJAKC9drMF9jy3+BHNUjW9NLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}