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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71361a6c9b777d34f1f5caa8d5700b03b0a07a55a8f13604379e25589b397819' 
  AND token = 'afedt3Q3b4F2X+UeNG82rPlCxyhehQkXzDS1tTfQoNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}