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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd225690eb647c95ff2cb39acb0d5037bce268e5bfd7a275f877e16ac5a0bc93e' 
  AND token = '9QpSC50R3n01++3wsE8k7L3z8MsNa/RMdIRC0ZC4kMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}