SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8049d1dc69061f60a160d689b95d45ea2c97a5b4b97d83d72a1a5dd2dc61bff' 
  AND token = '4yDCuZIAGxL5srypm5du+Y36agS0QWBVJnXC2LgSj5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}