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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b8c0171b20f94ab6349e642e80603d2b94a9689a8246b1a3bb6511d7a4f85b0' 
  AND token = 'wCWKLwCiCZWeshFmY9RkFoAECXxZ20uA8XdqQ9yf/1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}