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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c58966b258b26126abc7b53ef06e662d2f94b40b2ca48a5491220648181c333' 
  AND token = 'vgIvGmDsraUdSRXaExbdMB1oZz0MtoNDcs24lXWFj4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}