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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54528064f7abdd62db2666a236783167ecd69ceacb67c650299827ca97c25c42' 
  AND token = 'l1V2C78k3S2uz5OE+i2KnkRuv4t9U0wtpPUqByT8DcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}