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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ccef9f3a2d39a62e0b3acd2aabbb93cd58895902a64d001e76516ac6dd32a0' 
  AND token = 'jU2lxDwTpzOO2XF7ML3wUj4pk2W3rEFxAjHNTT0HEq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}