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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27faeff739e8b227dc575f5fa5cf220e8d2d26cc88e76b47833d432b432bd299' 
  AND token = 'etvJytdamvGvEquj8dJw+Zq70R7UlabXqcjdrjJi9Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}