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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b148a8cfc2bf0a4fe4771c2f4f2eb3a5abde45c34d378a8b5cb2787490e42c8a' 
  AND token = '2KvGPfZFiCmwZTCit3a6AWPNYwWZoMCPcIrxawZlwB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}