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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd043fb36c473e32cb29f42dd9428ef6cf9cbaba8e2675a412a6c77dd5a556d6e' 
  AND token = 'MMYTD8nBGM7NXiRrQE+R8JSEGd86fb5k+LZdtaU3lrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}