SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ae10c1e8955b210e6d84cc7fbf26344fd2ad71a0f44e97645fbbe7719f348c' 
  AND token = '6kYuJKiAf0yWrbq82/UB9aU1leg/uv3mMwGDuE+KseU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}