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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff4f4afc9b46ce045a9427a57f9a758aaf6383bf1beb5048057bdcb352c85bf' 
  AND token = 'OfKp/WyRi9cDsoIYqwUbafiRG1DjEORKoO9DgRji2W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}