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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7aee074fa50c397f6fb6546b8d4a8c690922b902963b2032dde1eaa32db65b3' 
  AND token = '4HtWdDKf1Y6NiP1VPcqFBw052D8h2YuwFQFrqA2XE4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}