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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff53caa48b2fa8a7b5e24bd98a3ef22821de117f758415ca0e7dafef3744745' 
  AND token = 'qKb1uLlSkyqYkQ+SrK2nlQyEnF3EFZbvcgmxaAIshhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}