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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3101f3f6c89c4071e33b8d24a3e6b08aaa9e65967cfc57f58ea5d728eafd2b1' 
  AND token = '8/MsYKXlW1K5/qCR21g7usSF7wYQb8nWRRYZKue8Bvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}