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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de2066172e79fccbdfbe4dabb204c3c8df782ffcd7785dce00577f81dd2ee10' 
  AND token = 'doJg9UiqHTBPCcHbBusUYzTGFwL6DoH1hEw+SlRHU70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}