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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0235d54a28b48b39aac049b5de0db10d5d7a63cd436c322c5db6e6dc11639be' 
  AND token = 'aIcFcLv3o6mZlbmYGKe1nNwyMR1f9zsdn6yWd7rHifc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}