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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f991d78050386e0f75da06c04bd550dd062735c887a91042370cf073baf2a9' 
  AND token = 'XNWGTq/WyDzMt5EUMgYJRwov5bpgAuRo3ebX2aRVGEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}